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  2. Cluster-randomised controlled trial - Wikipedia

    en.wikipedia.org/wiki/Cluster-randomised...

    Advantages of cluster-randomised controlled trials over individually randomised controlled trials include: The ability to study interventions that cannot be directed toward selected individuals (e.g., a radio show about lifestyle changes) and the ability to control for "contamination" across individuals (e.g., one individual's changing behaviors may influence another individual to do so).

  3. Clinical study design - Wikipedia

    en.wikipedia.org/wiki/Clinical_study_design

    Randomized controlled trial [5]. Blind trial [6]; Non-blind trial [7]; Adaptive clinical trial [8]. Platform Trials; Nonrandomized trial (quasi-experiment) [9]. Interrupted time series design [10] (measures on a sample or a series of samples from the same population are obtained several times before and after a manipulated event or a naturally occurring event) - considered a type of quasi ...

  4. Design effect - Wikipedia

    en.wikipedia.org/wiki/Design_effect

    Some sampling designs that could introduce generally greater than 1 include: cluster sampling (such as when there is correlation between observations), stratified sampling (with disproportionate allocation to the strata sizes), cluster randomized controlled trial, disproportional (unequal probability) sample (e.g. Poisson sampling), statistical ...

  5. Repeated measures design - Wikipedia

    en.wikipedia.org/wiki/Repeated_measures_design

    When such a trial is a repeated measures design, the subjects are randomly assigned to a sequence of treatments. A crossover clinical trial is a repeated-measures design in which each patient is randomly assigned to a sequence of treatments, including at least two treatments (of which one may be a standard treatment or a placebo ): Thus each ...

  6. Stepped-wedge trial - Wikipedia

    en.wikipedia.org/wiki/Stepped-wedge_trial

    In medicine, a stepped-wedge trial (or SWT) is a type of randomised controlled trial (RCT). An RCT is a scientific experiment that is designed to reduce bias when testing a new medical treatment , a social intervention , or another testable hypothesis .

  7. Crossover study - Wikipedia

    en.wikipedia.org/wiki/Crossover_study

    In medicine, a crossover study or crossover trial is a longitudinal study in which subjects receive a sequence of different treatments (or exposures). While crossover studies can be observational studies , many important crossover studies are controlled experiments , which are discussed in this article.

  8. Forest plot - Wikipedia

    en.wikipedia.org/wiki/Forest_plot

    The chart portion of the forest plot will be on the right hand side and will indicate the mean difference in effect between the test and control groups in the studies. A more precise rendering of the data shows up in number form in the text of each line, while a somewhat less precise graphic representation shows up in chart form on the right.

  9. Randomized controlled trial - Wikipedia

    en.wikipedia.org/wiki/Randomized_controlled_trial

    A randomized controlled trial (or randomized control trial; [2] RCT) is a form of scientific experiment used to control factors not under direct experimental control. Examples of RCTs are clinical trials that compare the effects of drugs, surgical techniques, medical devices , diagnostic procedures , diets or other medical treatments.