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Its use as a prophylactic treatment is supported by one clinical trial involving children with acute lymphoblastic leukaemia. [59] Other than this and one other clinical trial into its efficacy as a treatment for pneumocystis pneumonia, [ 60 ] data on its use in both the treatment and prevention of pneumocystis pneumonia is significantly lacking.
Therefore, the liver and kidney are the determining factors of these other hypersensitivity reactions; [10] alterations in kidney or liver functions may increase or decrease the frequencies of these reactions. One study has shown the allergic reaction rate to be about 3.0% over 359 courses of therapy. [11]
Symptoms of a kidney infection, on the other hand, are more systemic and include fever or flank pain usually in addition to the symptoms of a lower UTI. [10] Rarely, the urine may appear bloody. [7] Symptoms may be vague or non-specific at the extremities of age (i.e. in patients who are very young or old). [1] [11]
With treatment, outcomes are generally good in young adults. [3] [5] Among people over the age of 65 the risk of death is about 40%, though this depends on the health of the elderly person, the precise organism involved, and how quickly they can get care through a provider or in hospital. [5]
For as long as many of our readers can remember, a single orange has always appeared at the toe of their Christmas stockings. "I still place apples and oranges in my grandkids' stockings, in honor ...
Now, the Centers for Disease Control and Prevention (CDC) has released new guidance for the COVID-19 vaccine for those over 65 years old and/or immunocompromised.
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