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Another group [14] has reported that "age spots" taken from human skin biopsies of patients facial senile lentigo of Fitzpatrick skin type III or IV aged 55–62 are enriched with senescent fibroblasts compared to surrounding skin. The dark coloration appeared to be due to higher melanin levels and activity of tyrosinase in the senescent ...
Acanthosis nigricans is a medical sign characterised by brown-to-black, poorly defined, velvety hyperpigmentation of the skin. [1] It is usually found in body folds, [2] such as the posterior and lateral folds of the neck, the armpits, groin, navel, forehead and other areas. [1]
Dermatosis papulosa nigra (DPN) is a condition of many small, benign skin lesions on the face, a condition generally presenting on dark-skinned individuals. [1]: 638–9 DPN is extremely common, affecting up to 30% of Black people in the US. [2] From a histological perspective, DPN resembles seborrheic keratoses. [3]
Other benign skin lesions that may mimic acral lentiginous melanoma include: Lentigo (sun spots), Acral Nevi (moles), or Onychomycosis (fungal infection of the nail). These skin lesions can appear as dark brown spots, like ALM, but can be distinguished on close examination or dermatoscopy . [ 7 ]
Brighten dark spots: ... “Chaga mushroom has been shown to block the enzyme responsible for production of dark spots on the skin, the same target as ingredients like hydroquinone, kojic acid ...
Tinea nigra, also known as superficial phaeohyphomycosis and Tinea nigra palmaris et plantaris, [2] is a superficial fungal infection, a type of phaeohyphomycosis rather than a tinea, that causes usually a single 1–5 cm dark brown-black, non-scaly, flat, painless patch on the palms of the hands and the soles of the feet of healthy people. [1]