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  2. Pregabalin - Wikipedia

    en.wikipedia.org/wiki/Pregabalin

    Pregabalin, sold under the brand name Lyrica among others, is an anticonvulsant, analgesic, and anxiolytic amino acid medication used to treat epilepsy, neuropathic pain, fibromyalgia, restless legs syndrome, opioid withdrawal, and generalized anxiety disorder (GAD). [13] [17] [18] Pregabalin also has antiallodynic properties.

  3. Gabapentinoid - Wikipedia

    en.wikipedia.org/wiki/Gabapentinoid

    However, food has been found to substantially delay the absorption of pregabalin and to significantly reduce peak levels without affecting the bioavailability of the drug; T max values for pregabalin of 0.6 hours in a fasted state and 3.2 hours in a fed state (5-fold difference), and the C max is reduced by 25–31% in a fed versus fasted state ...

  4. Substance dependence - Wikipedia

    en.wikipedia.org/wiki/Substance_dependence

    Substance dependence, also known as drug dependence, is a biopsychological situation whereby an individual's functionality is dependent on the necessitated re-consumption of a psychoactive substance because of an adaptive state that has developed within the individual from psychoactive substance consumption that results in the experience of withdrawal and that necessitates the re-consumption ...

  5. Post-acute-withdrawal syndrome - Wikipedia

    en.wikipedia.org/wiki/Post-acute-withdrawal_syndrome

    A protracted withdrawal syndrome can occur with symptoms persisting for months to years after cessation of substance use. Benzodiazepines, opioids, alcohol, and any other drug may induce prolonged withdrawal and have similar effects, with symptoms sometimes persisting for years after cessation of use. Psychosis including severe anxiety and ...

  6. No. 3 Iowa State posts wire-to-wire win vs. No. 25 Baylor - AOL

    www.aol.com/no-3-iowa-state-posts-213240457.html

    Keshon Gilbert scored 16 points, grabbed 10 rebounds and dished five assists as No. 3 Iowa State pulled away from No. 25 Baylor 74-55 in a Big 12 Conference showdown Saturday in Ames, Iowa.

  7. Drug withdrawal - Wikipedia

    en.wikipedia.org/wiki/Drug_withdrawal

    Drug withdrawal, drug withdrawal syndrome, or substance withdrawal syndrome [1] is the group of symptoms that occur upon the abrupt discontinuation or decrease in the intake of pharmaceutical or recreational drugs. In order for the symptoms of withdrawal to occur, one must have first developed a form of drug dependence.

  8. 36-Year-Old Mother Begged Medical Staff to 'Not Let Me Die ...

    www.aol.com/lifestyle/36-old-mother-begged...

    A mother died shortly after the birth of her fifth child due to hospital staff failing to “appropriately escalate” signs of a peritoneal hemorrhage, according to a coroner’s report.

  9. Migrant teen killed, another injured, after being asked if ...

    www.aol.com/migrant-teens-stabbed-nyc-1...

    Officials say two migrant teens were victims in a New York City stabbing, one fatally, after the teens were asked if they spoke English and they responded that they didn't. Police say they were ...