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In the European Union it was approved in July 2016, for the treatment of chronic hepatitis C virus infection in adults. [7] The safety and efficacy of sofosbuvir/velpatasvir for a 12-week treatment was evaluated in three Phase III clinical trials of 1,558 subjects without cirrhosis or with compensated cirrhosis (mild cirrhosis). [13]
The initial recommended treatment depends on the type of hepatitis C virus, if the person has received previous hepatitis C treatment, and whether the person has cirrhosis. [88] Direct-acting antivirals are the preferred treatment and have been validated by testing for virus particles in patients' blood.
In advanced stages of chronic hepatitis C, cirrhosis—or scarring of the liver—is common. ... coupled with serious side effects that caused nearly one in two people to drop out of treatment ...
In the United States, G/P is used to treat adults and children aged 12 years and older or weighing at least 99 pounds with chronic hepatitis C virus (HCV) genotypes 1–6 and both without cirrhosis and with compensated cirrhosis who have not been previously treated for HCV (treatment-naïve).
Sofosbuvir is a once-daily oral nucleotide analogue inhibitor for the treatment of chronic hepatitis C virus Gilead Anti-Hep-C Treatment on the FDA Fast Track Skip to main content
Hepatitis B vaccine can prevent hepatitis B and the development of cirrhosis from it, but no vaccination against hepatitis C is available. [1] No specific treatment for cirrhosis is known, but many of the underlying causes may be treated by medications that may slow or prevent worsening of the condition. [3]
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