Search results
Results From The WOW.Com Content Network
Working together, biologists James Till and Ernest McCulloch made contributions to stem cell research by demonstrating the existence of multipotent stem cells in 1961. They helped lay the foundation for modern stem cell biology and regenerative medicine through their work while studying the effects of radiation on the bone marrow of mice at the Ontario Cancer Institute in Toronto.
Subsequently, Till chose to work with Ernest McCulloch at the University of Toronto. Thus, the older physician's insight was combined with the younger physicist's rigorous and thorough nature. In the early 1960s, McCulloch and Till started a series of experiments that involved injecting bone marrow cells into irradiated mice. They observed that ...
McCulloch was born in Toronto, Ontario, Canada on 27 April 1926, [2] [4] and was educated at Upper Canada College and the University of Toronto. [5] Ernest McCulloch received his MD in 1948 from the University of Toronto. Upon graduation, he began his education in research at the Lister Institute in London, England.
McCulloch and Till began a series of experiments in which bone marrow cells were injected into irradiated mice. They observed lumps in the spleens of the mice that were linearly proportional to the number of bone marrow cells injected. They hypothesized that each lump (colony) was a clone arising from a single marrow cell (stem cell).
The Canadian Stem Cell Foundation is an independent, non-profit organization established in 2008 and situated in Ottawa, Ontario. [1] Stem Cell science is a Canadian innovation through the discovery of stem cells by Drs. James Till and Ernest McCulloch.
Ernest McCulloch: Ingenious experiments that first identified a stem cell – the blood-forming stem cell – which set the stage for all current research on adult and embryonic stem cells. [51] James Till: Clinical Alec John Jeffreys
Sanford Jackson (B.Sc., M.Sc., Ph.D) – prominent biochemist, former biochemist-in-chief at the Toronto Hospital for Sick Children, inventor of the bilirubinometer; C. S. Holling (B.A., M.Sc. 1952) – ecologist and pioneer in ecological economics, director of the International Institute for Applied Systems Analysis in Vienna
Jack Hirsh CM FRSC (born January 7, 1935) is a Canadian clinician and scientist specializing in anticoagulant therapy and thrombosis.. Born in Melbourne, Australia, Hirsh is a graduate of the University of Melbourne Faculty of Medicine, Dentistry and Health Sciences.