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The presence of a "T-sign" at the inter-twin membrane-placental junction is indicative of monochorionic-diamniotic twins (that is, the junction between the inter-twin membrane and the external rim forms a right angle), whereas dichorionic twins present with a "lambda (λ) sign" (that is, the chorion forms a wedge-shaped protrusion into the ...
The human twin birth rate in the United States rose 76% from 1980 through 2009, from 9.4 to 16.7 twin sets (18.8 to 33.3 twins) per 1,000 births. [5] The Yoruba people have the highest rate of twinning in the world, at 45–50 twin sets (90–100 twins) per 1,000 live births, [6] [7] [8] possibly because of high consumption of a specific type of yam containing a natural phytoestrogen which may ...
Monoamniotic twins are identical or semi-identical twins that share the same amniotic sac within their mother's uterus. [1] Monoamniotic twins are always monochorionic and are usually termed Monoamniotic-Monochorionic ("MoMo" or "Mono Mono") twins. [1] [2] They share the placenta, but have two separate umbilical cords.
The word zygosity may also be used to describe the genetic similarity or dissimilarity of twins. [6] Identical twins are monozygotic, meaning that they develop from one zygote that splits and forms two embryos. Fraternal twins are dizygotic because they develop from two separate oocytes (egg cells) that are fertilized by two separate sperm.
Unlike monozygotic twins, dizygotic twins result from the fertilization of two eggs by two separate sperms within the same pregnancy. This causes the set of twins to have genetic variations, so their genetic information is unique from one another. In studies conducted between 1924 and 1976, there were more left-handed monozygotic twins.
In 1982, twins who were born with two different skin colors were discovered to be conceived as a result of heteropaternal superfecundation. [7] [5] In 1995, a young woman gave birth to diamniotic monochorionic twins, who were originally assumed to be monozygotic twins until a paternity suit led to a DNA test. This led to the discovery that the ...
An example of the clear phenotypic variability is a monozygotic twin study conducted by Jobling et al. (2010). Two monozygotic female twins had the same IRF6 mutation; however Twin A was born with a bilateral cleft lip, whereas Twin B had bilateral lip pits and no orofacial clefting. Both twins were diagnosed with VWS.
Identical twins have identical genomes in the immediate aftermath of twinning. About two-thirds of monozygotic twins share the same placenta, arising by cleavage before the fourth day of development; the other third have separate placentas because cleavage has taken place after the fourth day after choriogenesis has begun.