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Cough variant asthma (CVA), asthma where the only symptom is cough responsive to bronchodilator therapy, may be a T2-high asthma phenotype. CVA may be a precursor stage of other T2-high asthma phenotypes, as 30% of CVA patients are estimated to develop the classical asthma phenotype of wheeze and dyspnea.
Asthma phenotyping and endotyping has emerged as a novel approach to asthma classification inspired by precision medicine which separates the clinical presentations of asthma, or asthma phenotypes, from their underlying causes, or asthma endotypes. The best-supported endotypic distinction is the type 2-high/type 2-low distinction.
Most common causes for children include asthma, respiratory tract infections and GERD. An estimation of between one and 21% of children suffer from chronic cough. [2] [32] [33] Causes typically diagnosed include viral bronchitis, post-infectious cough, cough-variant asthma, upper airway cough syndrome, psychogenic cough and GERD.
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Cough, fever, and a stuffy or runny nose could accompany all four conditions. ... Here’s how to determine if it’s the JN.1 variant, RSV, the flu, or a cold instead. ... But RSV isn’t mild ...
The role for eNO in other conditions is even less well established compared to asthma. Since asthma can be a cause of chronic coughing (it may even be the sole manifestation, such as in cough-variant asthma), studies have looked at whether eNO can be used in the diagnosis of chronic cough. [18] [19] [20] [21]
Acute severe asthma; Airway remodelling; Alcohol-induced respiratory reactions; Allergies in children; Anti-asthmatic agent; Aspirin-exacerbated respiratory disease; Asthma; Asthma and Allergy Friendly; Asthma Life Impact Scale; Asthma phenotyping and endotyping; Asthma trigger; Asthma-COPD overlap; Asthma-related microbes; Asthmagen