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Alternatives to animal testing are the development and implementation of test methods that avoid the use of live animals. There is widespread agreement that a reduction in the number of animals used and the refinement of testing to reduce suffering should be important goals for the industries involved. [1]
The Johns Hopkins University Center for Alternatives to Animal Testing (CAAT) has worked with scientists, since 1981, to find new methods to replace the use of laboratory animals in experiments, reduce the number of animals tested, and refine necessary tests to eliminate pain and distress (the Three Rs as described in Russell and Burch's Principles of Humane Experimental Technique). [1]
ALTEX: Alternatives to Animal Experimentation is a quarterly peer-reviewed scientific journal covering alternatives to animal experimentation and related issues of bioethics, seeking to promote the replacement, reduction, and refinement of animal use in research (the "3Rs").
Pages in category "Alternatives to animal testing" The following 24 pages are in this category, out of 24 total. This list may not reflect recent changes. ...
The test can detect antipsychotic-like activity both in the case of dopamine D 2 receptor antagonists and in the case of drugs lacking D 2 receptor antagonism. [1] [2] [6] The occupancy of the D 2 receptor by antagonists of this receptor required to inhibit the CAR is around 65 to 80%, which is similar to the occupancy at which therapeutic antipsychotic effects occur in humans with these drugs.
The EPAA is a public-private partnership involving the European Commission (EC) and European industry sectors involved in the development of alternative approaches toward animal experimentation. The actions undertaken by the EPAA arise from communication and cooperation between services of the EC and industry, focused on regulatory compliance ...
Its goal was "to develop, validate, and promote laboratory methods and techniques that don't use animal test subjects". [1] It was the first centre in Canada dedicated to non-animal testing and the promotion of human-relevant alternatives. [2] [3] The CCAAM ceased operations on May 31, 2024 due to budget cuts at the University of Windsor. [4]
Founded by Ethel Thurston, PhD, in 1977, AFAAR's mission is to "promote and assist the development and use of alternatives to animals in science." Together, NEAVS and AFAAR have funded alternatives to common animal testing procedures such as the LD50 and Draize test for toxicity. Currently, AFAAR and NEAVS offer a one-year postdoctoral ...
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