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An atheroma, or atheromatous plaque, is an abnormal accumulation of material in the inner layer of an arterial wall. [ 1 ] [ 2 ] The material consists of mostly macrophage cells , [ 3 ] [ 4 ] or debris, containing lipids , calcium and a variable amount of fibrous connective tissue .
Calcification forms among vascular smooth muscle cells of the surrounding muscular layer, specifically in the muscle cells adjacent to atheromas and on the surface of atheroma plaques and tissue. [69] In time, as cells die, this leads to extracellular calcium deposits between the muscular wall and outer portion of the atheromatous plaques.
Generally an atheroma becomes vulnerable if it grows more rapidly and has a thin cover separating it from the bloodstream inside the arterial lumen. Tearing of the cover is called plaque rupture. However, a repeated atheroma rupture and healing is one of the mechanisms, perhaps the dominant one, that creates artery stenosis.
Plaque build-up often doesn’t cause symptoms, but it can block blood flow to vital organs like your heart. Coronary artery disease occurs when atherosclerosis affects the arteries supplying ...
In atherosclerosis, the inner endothelial layer of arteries [23] is stiffened by the deposition of an atheromatous plaque. [1] [11] [24] Atheromatous plaques, also called atherosclerotic plaques, are made of fats and lipid-laden macrophages. [20] Plaque deposition both physically narrows an artery and impairs the function of endothelial cells ...
Breakfast to help with blood vessel plaque, according to cardiologists Atherosclerosis (also known as clogged arteries) is one of the leading types of cardiovascular disease.
Atherosclerosis is a hardening of an artery specifically due to an atheromatous plaque. The term atherogenic is used for substances or processes that cause atherosclerosis. Micrograph showing hyaline arteriolosclerosis in the kidney. PAS stain.
Coronary artery disease (CAD), also called coronary heart disease (CHD), or ischemic heart disease (IHD), [13] is a type of heart disease involving the reduction of blood flow to the cardiac muscle due to a build-up of atheromatous plaque in the arteries of the heart. [5] [6] [14] It is the most common of the cardiovascular diseases. [15]