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Styrene is regarded as a "known carcinogen", especially in case of eye contact, but also in case of skin contact, of ingestion and of inhalation, according to several sources. [20] [33] [34] [35] Styrene is largely metabolized into styrene oxide in humans, resulting from oxidation by cytochrome P450.
Humans are exposed to toxic chemicals and microplastics at all stages in the plastics life cycle Microplastics effects on human health are of growing concern and an area of research. The tiny particles known as microplastics (MPs), have been found in various environmental and biological matrices, including air, water, food, and human tissues.
Residents near Cleves are being urged to leave their homes Tuesday afternoon because a rail car is leaking styrene. What to know about the chemical.
[6] [20] Overall, these studies showed that polystyrene nanoparticles did not affect cell viability. [6] [20] Similarly, it is important to consider polystyrene toxicity in human models. The use of polystyrene has been under scrutiny by various international and local agencies due to the effects of polystyrene on the environment.
Styrene oxide is a main metabolite of styrene in humans or animals, resulting from oxidation by cytochrome P450. It is considered possibly carcinogenic from gavaging significant amounts into mice and rats. [4] Styrene oxide is subsequently hydrolyzed in vivo to styrene glycol by epoxide hydrolase. [5]
2 Side effects in humans. 3 References. Toggle the table of contents. α-Methylstyrene. 16 languages. ... and effects on the central nervous system. [7] [8] References
IARC group 2B substances, mixtures and exposure circumstances are those that have been classified as "possibly carcinogenic to humans" by the International Agency for Research on Cancer (IARC) as [1] This category is used when there is limited evidence of carcinogenicity in humans and less than sufficient evidence of carcinogenicity in experimental animals.
This category is used most commonly for agents, mixtures and exposure circumstances for which the level of evidence of carcinogenicity is inadequate in humans and inadequate or limited in experimental animals. Exceptionally, agents (mixtures) for which the evidence of carcinogenicity is inadequate in humans, but sufficient in experimental ...