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In the liver, bilirubin is conjugated with glucuronic acid by the enzyme glucuronyltransferase, first to bilirubin glucuronide and then to bilirubin diglucuronide, making it soluble in water: the conjugated version is the main form of bilirubin present in the "direct" bilirubin fraction. Much of it goes into the bile and thus out into the small ...
Since these systems do not work by exchanging ions, like traditional water softeners do, one benefit claimed for the user is the elimination of the need to add salt to the system. Such systems do not remove minerals from the water itself. Rather, they can only alter the downstream effects that the mineral-bearing water would otherwise have.
Chloride cycle dealkalizers operate similar to sodium cycle cation water softeners. Like water softeners, dealkalizers contain ion-exchange resins that are regenerated with a concentrated salt solution - NaCl. In the case of a water softener, the cation exchange resin is exchanging sodium (the Na + ion of NaCl) for hardness minerals such as ...
Bilirubin is conjugated with glucuronic acid in the liver by the enzyme glucuronyltransferase, making it soluble in water. Much of it goes into the bile and thus out into the small intestine. Although 20% of the secreted bilirubinoid bile is reabsorbed by the small intestine, [2] conjugated
The human body uses glucuronidation to make a large variety of substances more water-soluble, and, in this way, allow for their subsequent elimination from the body through urine or feces (via bile from the liver). Hormones are glucuronidated to allow for easier transport around the body. Pharmacologists have linked drugs to glucuronic acid to ...
Bilirubin di-glucuronide is a conjugated form of bilirubin formed in bilirubin metabolism. [1] The hydrophilic character of bilirubin diglucuronide enables it to be water-soluble. It is pumped across the hepatic canalicular membrane into the bile by the transporter MRP2 .
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