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Fludrocortisone, sold under the brand name Florinef, among others, is a corticosteroid used to treat adrenogenital syndrome, postural hypotension, and adrenal insufficiency. [ 1 ] [ 2 ] [ 3 ] In adrenal insufficiency, it is generally taken together with hydrocortisone . [ 3 ]
In other projects Wikidata item; Appearance. move to sidebar hide Steroid ring ... Fludrocortisone = 9α-fluoro-11β,17α,21-trihydroxypregn-4-ene-3,20-dione;
Δ 7-Prednisolone 21-acetate; Alclometasone dipropionate; Amcinonide (triamcinolone acetate cyclopentanonide); Chloroprednisone acetate; Ciclometasone (a corticosteroid 21-[4-[(acetylamino)methyl]cyclohexyl]carboxylate ester)
Other names 9α-Fluoroprednisolone; Fluoroprednisolone; Deltafludrocortisone; δ-Fludrocortisone; δ-Fluorocortisone; 1-Dehydro-9α-fluorohydrocortisone; 9α-Fluoro-11β,17α,21-trihydroxypregna-1,4-diene-3,20-dione
Fludrocortisone (Florinef) is a synthetic mineralocorticoid. Hydrocortisone (cortisol) is typically used for replacement therapy, e.g. for adrenal insufficiency and congenital adrenal hyperplasia. [citation needed] Medical conditions treated with systemic corticosteroids: [2] [4]
Cortisone is a pregnene (21-carbon) steroid hormone.It is a naturally-occurring corticosteroid metabolite that is also used as a pharmaceutical prodrug. Cortisol is converted by the action of the enzyme corticosteroid 11-beta-dehydrogenase isozyme 2 into the inactive metabolite cortisone, particularly in the kidneys.
Trade names include Haelan (Typharm, UK) and Cordran (by Watson Pharmaceuticals, US). [2] [3] Fludroxycortide is available in ointment, cream and as an impregnated tape (Haelan tape, Cordran tape). Licensed indications in the United Kingdom include recalcitrant dermatoses. [4] [5]
Fluticasone; Clinical data; Other names: 6α,9α-Difluoro-11β,17α-dihydroxy-16α-methyl-21-thia-21-fluoromethylpregna-1,4-dien-3,20-dione; S-(Fluoromethyl)-6α,9α ...