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In 1996, a website was created expounding Pauling's treatment which it referred to as Pauling Therapy. Proponents of Pauling Therapy believe that heart disease can be treated and even cured using only lysine and Vitamin C and without drugs or heart operations. [139] Pauling's work on vitamin C in his later years generated much controversy.
Pauling argues that the loss of vitamin C synthesis first arose as a molecular disease, because of a genetic mutation that resulted in the loss of the biochemical capacity to make the vitamin, but because diets of the primate ancestors of humans consisted of high levels of vitamin C from plant sources, the loss of that biochemical mechanism was ...
The Pauling's book How to Live Longer and Feel Better, [92] first published in 1986, [93] was a bestseller and advocated taking more than 10 grams per day orally, thus approaching the amounts released by the liver directly into the circulation in other mammals: an adult goat, a typical example of a vitamin C–producing animal, will manufacture ...
In 1968, Linus Pauling first used the term orthomolecular. [6] [7] Hoffer's therapies focused on using niacin, among other nutrients, to treat what he diagnosed as acute schizophrenia based on an unaccepted test.
"Sickle Cell Anemia, a Molecular Disease" is a 1949 scientific paper by Linus Pauling, Harvey A. Itano, Seymour J. Singer and Ibert C. Wells that established sickle-cell anemia as a genetic disease in which affected individuals have a different form of the metalloprotein hemoglobin in their blood.
Megavitamin therapy is the use of large doses of vitamins, often many times greater than the recommended dietary allowance (RDA) in the attempt to prevent or treat diseases. Megavitamin therapy is typically used in alternative medicine by practitioners who call their approach orthomolecular medicine . [ 1 ]
Since the first claims of medical breakthroughs with vitamin C by Pauling and others, findings on the health effects of vitamin C have been controversial and contradictory. [34] [35] Pauling's claims have been criticised as overbroad. [36] Later research branched out into nutrients besides niacin and vitamin C, including essential fatty acids. [37]
One of Pauling's examples is olivine, M 2 SiO 4, where M is a mixture of Mg 2+ at some sites and Fe 2+ at others. The structure contains distinct SiO 4 tetrahedra which do not share any oxygens (at corners, edges or faces) with each other. The lower-valence Mg 2+ and Fe 2+ cations are surrounded by polyhedra which do share oxygens.