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The concept of the sentinel lymph node is important because of the advent of the sentinel lymph node biopsy technique, also known as a sentinel node procedure. This technique is used in the staging of certain types of cancer to see if they have spread to any lymph nodes, since lymph node metastasis is one of the most important prognostic signs .
Mokbel's clinical interests in the field of breast surgery include the early detection of breast cancer, breast ductoscopy, minimally-invasive breast surgery, sentinel node biopsy, skin-sparing mastectomy, breast reconstruction, cosmetic breast surgery, prevention of breast cancer, genetic predisposition, integrative oncology and the management of benign conditions including breast cysts ...
Lymph node biopsy is a test in which a lymph node or a piece of a lymph node is removed for examination under a microscope (see: biopsy). The lymphatic system is made up of several lymph nodes connected by lymph vessels. The nodes produce white blood cells (lymphocytes) that fight infections. When an infection is present, the lymph nodes swell ...
A sentinel node biopsy can establish cancer staging of the axilla if there are positive lymph nodes present. [5] It is also less risky than performing a lymphadenectomy, having fewer side effects and a much lower chance of causing lymphedema. [5] If cancer is not present in the sentinel lymph nodes, then the axillary lymph node dissection ...
To locate the draining lymph nodes or sentinel lymph nodes from a breast cancer tumour, a Technetium-99m based radiopharmaceutical is common. This may be a nanocolloid or sestamibi . [ 7 ] Although imaging with a gamma camera may also take place, the idea of a small gamma probe is that it can be used to identify lymph nodes (or other sites ...
Such spread typically results in Troisier's sign, which is the finding of an enlarged, hard Virchow's node. [1] The left supraclavicular nodes are the classical Virchow's node because they receive lymphatic drainage of most of the body (from the thoracic duct) and enters the venous circulation via the left subclavian vein. The metastasis may ...
The occipital lymph nodes, one to three in number, are located on the back of the head close to the margin of the trapezius and resting on the insertion of the semispinalis capitis.
The most common cause of enlargement of the submental lymph nodes are infections (including viral infections (mononucleosis, Epstein-Barr virus infection, and cytomegaloviral infections), toxoplasmosis, and dental infections (e.g. periodontitis)).