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The use of zinc sulfate supplements together with oral rehydration therapy decreases the number of bowel movements and the time until the diarrhea stops. [2] Its use in this situation is recommended by the World Health Organization. [2] There is some evidence zinc is effective in reducing hepatic and neurological symptoms of Wilson's disease. [8]
The ZMA formula is composed of zinc monomethionine aspartate (30 mg), magnesium aspartate (450 mg), and vitamin B 6 as pyridoxine hydrochloride (10.5 mg). The manufacturer recommends that ZMA be taken 30 – 60 minutes before bedtime with an empty stomach to help synchronize absorption with sleep.
The trihydrate salt is obtained as a reddish-brown precipitate by adding two equivalents of potassium cyanide to a cobalt salt solution: [3]. CoCl 2 (H 2 O) 6 + 2 KCN → Co(CN) 2 + 2 KCl + 6 H 2 O
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Zinc deficiency is defined either as insufficient zinc to meet the needs of the body, or as a serum zinc level below the normal range. However, since a decrease in the serum concentration is only detectable after long-term or severe depletion, serum zinc is not a reliable biomarker for zinc status. [ 1 ]