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This was the first federal programme to promote drug discovery for cancer – unlike now, most pharmaceutical companies were not yet interested in developing anticancer drugs. The CCNSC developed the methodologies and crucial tools (like cell lines and animal models) for chemotherapeutic development.
This rivalry and opposition to Dr. Coley leads to the disuse of immunotherapy for cancer, in favor of Dr. Ewing's preferred radiation therapy [9] 1939 – American Dr. Charles Huggins uses synthetic hormone therapy to treat prostate cancer [10] 1942 – First chemotherapy drug mustine used to treat cancer [11]
The first cause of cancer was identified by British surgeon Percivall Pott, who discovered in 1775 that cancer of the scrotum was a common disease among chimney sweeps. [ citation needed ] The work of other individual physicians led to various insights, but when physicians started working together they could draw firmer conclusions.
In 1906 Ehrlich became the director of the Georg Speyer House in Frankfurt, a private research foundation affiliated with his institute. Here he discovered in 1909 the first drug to be targeted against a specific pathogen: Salvarsan, a treatment for syphilis, which was at that time one of the most lethal and infectious diseases in Europe. In ...
Yellapragada Subbarow [a] (12 January 1895 – 8 August 1948) was an Indian American biochemist who discovered the function of adenosine triphosphate (ATP) as an energy source in the cell, [1] developed methotrexate for the treatment of cancer and led the department at Lederle laboratories in which Benjamin Minge Duggar discovered chlortetracycline in 1945.
Pliny the Elder, who lived from 23–79 CE, first gave a name to what we now call pills, calling them pilula. [2] Pliny also wrote Naturalis Historia a collection of 38 books and the first pharmacopoea. Pedanius Dioscorides wrote De Materia Medica (c. 40 – 90 CE); this book dominated the area of drug knowledge for some 1500 years until the ...
Gertrude Elion, working mostly with a group of fewer than 50 people on purine analogues, contributed to the discovery of the first anti-viral; the first immunosuppressant (azathioprine) that allowed human organ transplantation; the first drug to induce remission of childhood leukemia; pivotal anti-cancer treatments; an anti-malarial; an anti ...
Emil J. Freireich (March 16, 1927 – February 1, 2021) [1] was an American hematologist, oncologist, and cancer biologist. He was recognized as a pioneer in the treatment of cancer and use of chemotherapy and is often known as the father of modern leukemia therapy. [2]