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Midazolam, sold under the brand name Versed among others, is a benzodiazepine medication used for anesthesia, premedication before surgical anesthesia, and procedural sedation, and to treat severe agitation. [12] It induces sleepiness, decreases anxiety, and causes anterograde amnesia. [12]
In medicine, specifically in end-of-life care, palliative sedation (also known as terminal sedation, continuous deep sedation, or sedation for intractable distress of a dying patient) is the palliative practice of relieving distress in a terminally ill person in the last hours or days of a dying person's life, usually by means of a continuous intravenous or subcutaneous infusion of a sedative ...
Mayo Clinic Health System - Eau Claire: Eau Claire: Wisconsin: II Mayo Clinic Health System - La Crosse: La Crosse: Wisconsin: III SSM Health Saint Mary's Hospital – Madison: Madison: Wisconsin: II Mercyhealth Hospital and Trauma Center - Janesville: Janesville: Wisconsin: II St. Vincent Hospital: Green Bay: Wisconsin: II ThedaCare Regional ...
Additionally, IV sedation is frequently administered as a concoction of several agents including those previously mentioned for induction and maintenance of anesthesia, as well as a benzodiazepine (usually midazolam, but temazepam or flunitrazepam are also used via the oral route [4]) and a narcotic/systemic analgesic such as demerol or fentanyl.
Midazolam collects in the body's fatty tissues, so a possible complication includes prolonged sedation. As a result, the elderly, the obese, and those with kidney or liver disease are more vulnerable to prolonged sedation with midazolam. Respiratory depression is also associated with midazolam when given in high doses.
The most commonly utilized benzodiazepine is Midazolam, which is characterized by a rapid onset and short duration. Midazolam is effective in reducing preoperative anxiety, including separation anxiety in children. [28] It also provides mild sedation, sympathicolysis, and anterograde amnesia. [6]