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M2-PK, as measured in feces, is a potential tumor marker for colorectal cancer. When measured in feces with a cutoff value of 4 U/ml, its sensitivity has been estimated to be 85% (with a 95% confidence interval of 65 to 96%) for colon cancer and 56% (confidence interval 41–74%) for rectal cancer. [1] Its specificity is 95%. [2]
The CEA blood test is not reliable for diagnosing cancer or as a screening test for early detection of cancer. [8] Most types of cancer do not result in a high CEA level. [9] Serum from individuals with colorectal carcinoma often has higher levels of CEA than healthy individuals (above approximately 2.5ng/mL). [10]
The gold standard of early detection of colon polyp/cancer is the invasive colonoscopy, but with high expense about $557, while tumor marker M2-PK Test expense only about $15-$25. The invasive colonoscopy makes acceptance of it low among patients, so relatively cheap non-invasive M2-PK Test is a good choice for detection early polyp/cancer. [2]
The Food and Drug Administration (FDA) has recently approved a blood test screening for colorectal cancer that has an over 83% success rate at detecting the presence of this form of cancer.
The Food and Drug Administration on Monday approved Guardant Health’s blood test, called Shield, to screen for colon cancer. The test isn't meant to replace colonoscopies, but is generating ...
A blood test for colon cancer performed well in a study published Wednesday, offering a new kind of screening for a leading cause of cancer deaths. The test looks for DNA fragments shed by tumor ...