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Alcohol intoxication leads to negative health effects due to the recent drinking of large amount of ethanol (alcohol). [6] [20] When severe it may become a medical emergency. Some effects of alcohol intoxication, such as euphoria and lowered social inhibition, are central to alcohol's desirability. [21]
Alcohol use disorder (AUD) is defined as a medical condition characterized by an impaired ability to stop or control alcohol use despite adverse social, occupational, or health consequences. [124] Excessive alcohol use can lead to health-related illness and continuous alcohol engagement can ultimately lead to death.
Ethanol, when used to treat or prevent methanol and/or ethylene glycol toxicity, competes with other alcohols for the alcohol dehydrogenase enzyme, lessening metabolism into toxic aldehyde and carboxylic acid derivatives, and reducing the more serious toxic effects of the glycols when crystallized in the kidneys.
Regarding inhalation, early experiments with animals showed that it was possible to produce significant BAC levels comparable to those obtained by injection, by forcing the animal to breathe alcohol vapor. [82] In humans, concentrations of ethanol in air above 10 mg/L caused initial coughing and smarting of the eyes and nose, which went away ...
Alcohol is responsible in the world for 2.6 million deaths and results in disability in approximately 115.9 million people. Approximately 40 percent of the 115.9 million people disabled through alcohol abuse are disabled due to alcohol-related neuropsychiatric disorders. [96] Alcohol abuse is highly associated with adolescent suicide.
The level of ethanol consumption that minimizes the risk of disease, injury, and death is subject to some controversy. [16] Several studies have found a J-shaped relationship between alcohol consumption and health, [17] [18] [2] [19] meaning that risk is minimized at a certain (non-zero) consumption level, and drinking below or above this level increases risk, with the risk level of drinking a ...