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Alcohol intoxication leads to negative health effects due to the recent drinking of large amount of ethanol (alcohol). [6] [20] When severe it may become a medical emergency. Some effects of alcohol intoxication, such as euphoria and lowered social inhibition, are central to alcohol's desirability. [21]
Alcohol is known to potentiate the insulin response of the human body to glucose, which, in essence, "instructs" the body to convert consumed carbohydrates into fat and to suppress carbohydrate and fat oxidation. [63] [64] Ethanol is directly processed in the liver to acetyl CoA, the same intermediate product as in glucose metabolism.
Ethanol, when used to treat or prevent methanol and/or ethylene glycol toxicity, competes with other alcohols for the alcohol dehydrogenase enzyme, lessening metabolism into toxic aldehyde and carboxylic acid derivatives, and reducing the more serious toxic effects of the glycols when crystallized in the kidneys.
To engage in alcohol consumption and the development of an alcohol use disorder appear to be common to primates, and is not a specific human phenomenon. [9] Humans have access to alcohol in far greater quantity than non-human primates, and the availability increased, particularly with the development of agriculture. [10]
Understanding the distinctions between alcohol intolerance and alcohol allergy is crucial for proper alleviation of symptoms. Alcohol intolerance results from metabolic challenges related to enzyme function, while alcohol allergy involves the immune response. Recognizing these differences can help individuals avoid triggers and seek appropriate ...
Alcohol-related brain damage [1] [2] alters both the structure and function of the brain as a result of the direct neurotoxic effects of alcohol intoxication or acute alcohol withdrawal. Increased alcohol intake is associated with damage to brain regions including the frontal lobe , [ 3 ] limbic system , and cerebellum , [ 4 ] with widespread ...
Regarding inhalation, early experiments with animals showed that it was possible to produce significant BAC levels comparable to those obtained by injection, by forcing the animal to breathe alcohol vapor. [82] In humans, concentrations of ethanol in air above 10 mg/L caused initial coughing and smarting of the eyes and nose, which went away ...
Alcohol dependence is a previous (DSM-IV and ICD-10) psychiatric diagnosis in which an individual is physically or psychologically dependent upon alcohol (also chemically known as ethanol). In 2013, it was reclassified as alcohol use disorder in DSM-5 , [ 1 ] which combined alcohol dependence and alcohol abuse into this diagnosis.