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Atypical endometrial hyperplasia (simple or complex) - Simple or complex architectural changes, with worrisome (atypical) changes in gland cells, including cell stratification, tufting, loss of nuclear polarity, enlarged nuclei, and an increase in mitotic activity. These changes are similar to those seen in true cancer cells, but atypical ...
Atypical endometrial hyperplasia may represent an early neoplastic process which can lead to endometrial adenocarcinoma. [20] The development of endometrial adenocarcinoma from endometrial hyperplasia is a typical example of how the effects of pathologic hyperplasia can lead to neoplasia, and females who exhibit hyperplasia of the endometrium ...
Metropathia haemorrhagica, also known as metropathia haemorrhagica cystica, is a menstrual disorder which is defined as a specialized type of anovulatory dysfunctional uterine bleeding associated with endometrial hyperplasia and intermenstrual bleeding.
Uterine hyperplasia, or enlarged uterus, is a medical symptom in which the volume and size of the uterus in a female is abnormally high. It can be a symptom of medical conditions such as adenomyosis , uterine fibroids , ovarian cysts , and endometrial cancer .
(E): endometrial atypical hyperplasia (Left: HE × 10) and endometrial atypical cells (Right: HE × 200) (F) endometrial carcinoma (Left: HE × 400) and endometrial cancer cells (Right: HE × 400). Chorionic tissue can result in marked endometrial changes, known as an Arias-Stella reaction, that have an appearance similar to cancer. [15]
They are a subset of a larger mixed group of lesions previously called "endometrial hyperplasia". [ 2 ] [ 3 ] The EIN diagnostic schema is intended to replace the previous " endometrial hyperplasia " classification as defined by the World Health Organization in 1994, which have been separated into benign (benign endometrial hyperplasia) and ...
Detection by ultrasonography can be difficult, particularly when there is endometrial hyperplasia (excessive thickening of the endometrium). [2] Larger polyps may be missed by curettage. [10] Endometrial polyps can be solitary or occur with others. [11] They are round or oval and measure between a few millimeters and several centimeters in ...
It is distinguished from hyperplasia, in which the cells remain approximately the same size but increase in number. [2] Although hypertrophy and hyperplasia are two distinct processes, they frequently occur together, such as in the case of the hormonally induced proliferation and enlargement of the cells of the uterus during pregnancy.