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The tongue may show a diffuse, smooth generalized enlargement. [3] The face may show maxillary hypoplasia causing relative mandibular prognathism. Apparent macroglossia can also occur in Down syndrome. [8] The tongue has a papillary, fissured surface. [3] Macroglossia may be a sign of hypothyroid disorders.
When someone has hypothyroidism, symptoms may range from mild to severe, Alexander says. Hypothyroidism often slows metabolism, causing your body to burn fewer calories than normal, ...
The degree of iodine deficiency was milder and manifested primarily as thyroid enlargement rather than severe mental and physical impairment. In Switzerland, for example, where soil does not contain a large amount of iodine, cases of congenital iodine deficiency syndrome were very abundant and even considered genetically caused.
Neonatal hypothyroidism has been reported in cases of infants exposed to lithium, a mood stabilizer used to treat bipolar disorder, in utero. [4] In some instances, hypothyroidism detected by screening may be transient. One common cause of this is the presence of maternal antibodies that temporarily impair thyroid function for several weeks. [5]
Thyroid disorders are broken into two types: hypothyroidism and hyperthyroidism. Symptoms are trouble losing or gaining weight, hair loss, and more.
Myxoedema is responsible for the thickening of the tongue and the laryngeal and pharyngeal mucous membranes, which results in thick slurred speech and hoarseness, both of which are seen commonly in hypothyroidism. [citation needed] The increased deposition of glycosaminoglycan is not fully understood, however, two mechanisms predominate: