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Rupture of a papillary muscle will cause acute mitral regurgitation. [citation needed] The rupture will most often occur near the edge of the necrotic myocardium where it abuts healthy (but hyperemic) myocardium where the inflammatory response is at its greatest. Further, the rupture will occur in an area of greatest shear stress. Within the ...
The role of these macrophages is the removal of necrotic myocytes. However, these cells are directly involved in the weakening of the tissue, leading to complications such as a ventricular free wall rupture, intraventricular septum rupture, or a papillary muscle rupture. At a gross anatomical level, this staged is marked by a yellow pallor.
Papillary muscle rupture can be caused by a myocardial infarction, and dysfunction can be caused by ischemia. Rarely, blunt chest trauma can be the cause of papillary muscle rupture, resulting from the sudden deceleration or compression of the heart. [4] Complications may lead to worsening of mitral regurgitation. [5]
In acute MR secondary to a mechanical defect in the heart (i.e., rupture of a papillary muscle or chordae tendineae), the treatment of choice is mitral valve surgery. If the patient is hypotensive prior to the surgical procedure, an intra-aortic balloon pump may be placed in order to improve perfusion of the organs and to decrease the degree of MR.
Parachute mitral valve occurs when all the chordae tendineae of the mitral valve attach to a single papillary muscle. [9] [10] [11] This causes mitral valve stenosis at an early age. [10] It is a rare congenital heart defect. [11] Although it often causes mitral insufficiency, it may not present any symptoms. [10]
Whereas, disease of the valve is categorized to primary mitral regurgitation or secondary mitral regurgitation based on the regurgitant etiology. Type II pertains to excessive leaflet motion leading to leaflet prolapse. Common causes include, but is not limited to, Barlow disease, myxomatous degeneration, inflammation, and papillary muscle rupture.
Rupture(free ventricular wall/ ventricular septum/ papillary muscles) Tamponade Heart failure (acute or chronic) Valve disease Aneurysm of Ventricles Dressler's Syndrome thromboEmbolism (mural thrombus) Recurrence/ mitral Regurgitation [5]
The artery supplies the anterior region of the left ventricle, including: the anterolateral myocardium, apex, anterior interventricular septum, and anterolateral papillary muscle. [8] The LAD typically supplies 45–55% of the left ventricle and is therefore considered the most critical vessel in terms of myocardial blood supply.