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MPH is given by (mother’s height + father’s height) divided by 2. MPH is unisex. Boys need an upward correction, girls need a downward correction. In view of an average height difference between adult men and women of 13 cm, TH for boys is usually given by MPH + 6.5cm, TH for girls by MPH - 6.5cm.
During Tanner V, females stop growing and reach their adult height. Usually, this happens in their mid teens at 14 or 15 years for females. Males also stop growing and reach their adult height during Tanner V; usually this happens in their late teens at 16 to 17 years, [medical citation needed] but can be a lot later, even into the early 20s.
Growth hormone deficiencies have also been correlated with WHRs in prepubertal children; the specific baseline body statistics, such as WHRs, of pre-pubertal children with growth hormone deficiencies can predict growth response effectiveness to artificial growth hormone therapies, such as rhGH treatments.
In terms of height growth and height growth related to bone age, average females stop growing taller two years earlier than average males. Peak height velocity (PHV) occurs at the average age of 11 years for girls and at the average age of 13 years for boys. [29]
Genes for human growth hormone, known as growth hormone 1 (somatotropin; pituitary growth hormone) and growth hormone 2 (placental growth hormone; growth hormone variant), are localized in the q22-24 region of chromosome 17 [7] [8] and are closely related to human chorionic somatomammotropin (also known as placental lactogen) genes.
Diagnosis involves blood tests to measure growth hormone levels. [2] Treatment is by growth hormone replacement using synthetic human growth hormone. [1] The frequency of the condition is unclear. [2] Most cases are initially noticed in children. [1] The genetic forms of this disease are estimated to affect about 1 in 7,000 people. [3]
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