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bedinvetmab - nerve growth factor inhibitor monoclonal antibody used for osteoarthritis in dogs; benazepril – ACE-inhibitor used in heart failure, hypertension, chronic kidney failure and protein-losing nephropathy; bethanechol – stimulates bladder contractions, tranquilizer, makes the patient feel no pain; bexagliflozin - oral antidiabetic ...
Bethanechol is a parasympathomimetic choline carbamate that selectively stimulates muscarinic receptors without any effect on nicotinic receptors. Unlike acetylcholine , bethanechol is not hydrolyzed by cholinesterase and will therefore have a long duration of action.
"Anti-cholinergic" side-effects, including urinary hesitancy/retention, may be treated/reversed with bethanechol and/or other acetylcholine-agonists. [48] [49] [50] Bethanechol may also be able to alleviate the sexual-dysfunction symptoms which may occur in the context of tricyclic-antidepressant treatment. [51] [52] [53]
Acetylcholine Acetylcholinesterase Acetylcholinesterase inhibition. Acetylcholinesterase inhibitors (AChEIs) also often called cholinesterase inhibitors, [1] inhibit the enzyme acetylcholinesterase from breaking down the neurotransmitter acetylcholine into choline and acetate, [2] thereby increasing both the level and duration of action of acetylcholine in the central nervous system, autonomic ...
Bethanechol +++--Used in bladder and gastrointestinal hypotonia. Muscarine +++--Natural alkaloid found in certain mushrooms. Cause of one form of mushroom poisoning Nicotine-+++-Natural alkaloid found in the tobacco plant. Pilocarpine ++--Used in glaucoma. Oxotremorine ++ + [12]-Used in research to induce symptoms of Parkinson's disease.
A parasympathomimetic drug, sometimes called a cholinomimetic drug [1] or cholinergic receptor stimulating agent, [2] is a substance that stimulates the parasympathetic nervous system (PSNS).
Physostigmine, an acetylcholinesterase inhibitor, can be used to treat glaucoma and delayed gastric emptying.Because it enhances the transmission of acetylcholine signals in the brain and can cross the blood–brain barrier, physostigmine salicylate is used to treat anticholinergic poisoning (that is, poisoning by substances that interfere with the transmission of acetylcholine signaling, such ...
Bethanechol is a muscarinic agonist.It is included in the therapy for underactive bladder with poor contraction of detrusor muscle. [2] Since contraction of detrusor muscle in the bladder is controlled by the parasympathetic nervous system, Bethanechol can bind to muscarinic receptors to stimulate activation of the parasympathetic nervous system and restore contraction of detrusor muscle.