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  2. Intracellular pH - Wikipedia

    en.wikipedia.org/wiki/Intracellular_pH

    The pH i plays a critical role in membrane transport and other intracellular processes. In an environment with the improper pH i, biological cells may have compromised function. [1] [2] Therefore, pH i is closely regulated in order to ensure proper cellular function, controlled cell growth, and normal cellular processes. [3]

  3. Acidosis - Wikipedia

    en.wikipedia.org/wiki/Acidosis

    The use of acidosis for a low pH creates an ambiguity in its meaning. The difference is important where a patient has factors causing both acidosis and alkalosis, wherein the relative severity of both determines whether the result is a high, low, or normal pH. [citation needed] Alkalemia occurs at a pH over 7.45.

  4. Lactic acidosis - Wikipedia

    en.wikipedia.org/wiki/Lactic_acidosis

    The result can be detected with high levels of lactate and low levels of bicarbonate. This is usually considered the result of illness but also results from strenuous exercise. The effect on pH is moderated by the presence of respiratory compensation. Lactic acidosis is usually the result of tissue hypoxia which is not the same as arterial hypoxia.

  5. Acid–base homeostasis - Wikipedia

    en.wikipedia.org/wiki/Acid–base_homeostasis

    An acid-base diagram for human plasma, showing the effects on the plasma pH when P CO 2 in mmHg or Standard Base Excess (SBE) occur in excess or are deficient in the plasma [23] Acid–base imbalance occurs when a significant insult causes the blood pH to shift out of the normal range (7.32 to 7.42 [16]).

  6. Ion trapping - Wikipedia

    en.wikipedia.org/wiki/Ion_trapping

    In cell biology, ion trapping is the build-up of a higher concentration of a chemical across a cell membrane due to the pKa value of the chemical and difference of pH across the cell membrane. [1] [2] This results in basic chemicals accumulating in acidic bodily fluids such as the cytosol, and acidic chemicals accumulating in basic fluids.

  7. Bohr effect - Wikipedia

    en.wikipedia.org/wiki/Bohr_effect

    That is, the Bohr effect refers to the shift in the oxygen dissociation curve caused by changes in the concentration of carbon dioxide or the pH of the environment. Since carbon dioxide reacts with water to form carbonic acid, an increase in CO 2 results in a decrease in blood pH, [2] resulting in hemoglobin proteins releasing their load of ...