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Bioburden is normally defined as the number of bacteria living on a surface that has not been sterilized. [ 1 ] The term is most often used in the context of bioburden testing, also known as microbial limit testing, which is performed on pharmaceutical products and medical products for quality control purposes.
Colony-forming units are used to quantify results in many microbiological plating and counting methods, including: The pour plate method wherein the sample is suspended in a Petri dish using molten agar cooled to approximately 40–45 °C (just above the point of solidification to minimize heat-induced cell death).
BOD test bottles at the laboratory of a wastewater treatment plant. Biochemical oxygen demand (also known as BOD or biological oxygen demand) is an analytical parameter representing the amount of dissolved oxygen (DO) consumed by aerobic bacteria growing on the organic material present in a water sample at a specific temperature over a specific time period.
The Streeter–Phelps equation is also known as the DO sag equation. This is due to the shape of the graph of the DO over time. The biological oxygen demand (BOD) and dissolved oxygen (DO) curves in a river flowing right reaching equilibrium after a continuous input of high BOD influent is added into the river at x = 15 m and t = 0 s.
In microbiology, sterility assurance level (SAL) is the probability that a single unit that has been subjected to sterilization nevertheless remains nonsterile.. It is never possible to prove that all organisms have been destroyed, as the likelihood of survival of an individual microorganism is never zero.
2011 F&W Best New Chef Jamie Bissonnette uses a similar stovetop method, popping the kernels in butter in a Dutch oven, but with one major twist: whole garlic cloves.
The normal distribution is NOT assumed nor required in the calculation of control limits. Thus making the IndX/mR chart a very robust tool. Thus making the IndX/mR chart a very robust tool. This is demonstrated by Wheeler using real-world data [ 4 ] , [ 5 ] and for a number of highly non-normal probability distributions.
In microbiology, in the context of a sterilization procedure, the D-value or decimal reduction time (or decimal reduction dose) is the time (or dose of an antimicrobial drug) required, at a given condition (e.g. temperature) or set of conditions, to achieve a one-log reduction, that is, to kill 90% of relevant microorganisms. [1]