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  2. Baclofen - Wikipedia

    en.wikipedia.org/wiki/Baclofen

    Baclofen, sold under the brand name Lioresal among others, is a medication used to treat muscle spasticity, such as from a spinal cord injury or multiple sclerosis. [8] [9] It may also be used for hiccups and muscle spasms near the end of life, [9] and off-label to treat alcohol use disorder [10] [11] or opioid withdrawal symptoms. [12]

  3. Equianalgesic - Wikipedia

    en.wikipedia.org/wiki/Equianalgesic

    An equianalgesic chart is a conversion chart that lists equivalent doses of analgesics (drugs used to relieve pain). Equianalgesic charts are used for calculation of an equivalent dose (a dose which would offer an equal amount of analgesia) between different analgesics. [1]

  4. Therapeutic index - Wikipedia

    en.wikipedia.org/wiki/Therapeutic_index

    The therapeutic window (or pharmaceutical window) of a drug is the range of drug dosages which can treat disease effectively without having toxic effects. [25] Medication with a small therapeutic window must be administered with care and control, frequently measuring blood concentration of the drug, to avoid harm.

  5. FDA Accepts Eliquis® (apixaban) Supplemental New Drug ... - AOL

    www.aol.com/2013/07/11/fda-accepts-eliquis...

    FDA Accepts Eliquis ® (apixaban) Supplemental New Drug Application for Review for Prophylaxis of Deep Vein Thrombosis Following Hip Or Knee Replacement Surgery PRINCETON, N.J. & NEW YORK ...

  6. Threshold dose - Wikipedia

    en.wikipedia.org/wiki/Threshold_dose

    Threshold dose is the minimum dose of drug that triggers minimal detectable biological effect in an animal. [1] At extremely low doses, biological responses are absent for some of the drugs. The increase in dose above threshold dose induces an increase in the percentage of biological responses. [ 2 ]

  7. Apixaban - Wikipedia

    en.wikipedia.org/wiki/Apixaban

    In July 2022, the Canadian generic drug company, Apotex Inc., obtained approval for marketing of apixaban. [40] [41] Pfizer reported revenue of US$6.747 billion for Eliquis in 2023. [42] Apixaban is one of ten medications covered by price negotiations in the US under the Inflation Reduction Act.

  8. Dosage (pharmacology) - Wikipedia

    en.wikipedia.org/wiki/Dosage_(pharmacology)

    Dosage typically includes information on the number of doses, intervals between administrations, and the overall treatment period. [3] For example, a dosage might be described as "200 mg twice daily for two weeks," where 200 mg represents the individual dose, twice daily indicates the frequency, and two weeks specifies the duration of treatment.

  9. Effective dose (pharmacology) - Wikipedia

    en.wikipedia.org/wiki/Effective_dose_(pharmacology)

    In pharmacology, an effective dose (ED) or effective concentration (EC) is the dose or concentration of a drug that produces a biological response. [ 1 ] [ 2 ] The term "effective dose" is used when measurements are taken in vivo , while "effective concentration" is used when the measurements are taken in vitro .