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  2. Action potential - Wikipedia

    en.wikipedia.org/wiki/Action_potential

    An action potential occurs when the membrane potential of a specific cell rapidly rises and falls. [1] This depolarization then causes adjacent locations to similarly depolarize. Action potentials occur in several types of excitable cells, which include animal cells like neurons and muscle cells, as well as some plant cells.

  3. All-or-none law - Wikipedia

    en.wikipedia.org/wiki/All-or-none_law

    The magnitude of the action potential set up in any single nerve fibre is independent of the strength of the exciting stimulus, provided the latter is adequate. An electrical stimulus below threshold strength fails to elicit a propagated spike potential. If it is of threshold strength or over, a spike (a nervous impulse) of maximum magnitude is ...

  4. Node of Ranvier - Wikipedia

    en.wikipedia.org/wiki/Node_of_Ranvier

    The action potential travels from one location in the cell to another, but ion flow across the membrane occurs only at the nodes of Ranvier. As a result, the action potential signal jumps along the axon, from node to node, rather than propagating smoothly, as they do in axons that lack a myelin sheath.

  5. Goldman equation - Wikipedia

    en.wikipedia.org/wiki/Goldman_equation

    The ionic charge determines the sign of the membrane potential contribution. During an action potential, although the membrane potential changes about 100mV, the concentrations of ions inside and outside the cell do not change significantly. They are always very close to their respective concentrations when the membrane is at their resting ...

  6. Depolarization - Wikipedia

    en.wikipedia.org/wiki/Depolarization

    The surge of depolarization traveling from the axon hillock to the axon terminal is known as an action potential. Action potentials reach the axon terminal, where the action potential triggers the release of neurotransmitters from the neuron. The neurotransmitters that are released from the axon continue on to stimulate other cells such as ...

  7. Quantitative models of the action potential - Wikipedia

    en.wikipedia.org/wiki/Quantitative_models_of_the...

    Figure FHN: To mimick the action potential, the FitzHugh–Nagumo model and its relatives use a function g(V) with negative differential resistance (a negative slope on the I vs. V plot). For comparison, a normal resistor would have a positive slope, by Ohm's law I = GV, where the conductance G is the inverse of resistance G=1/R.

  8. Refractory period (physiology) - Wikipedia

    en.wikipedia.org/wiki/Refractory_period_(physiology)

    An action potential consists of three phases. Phase one is depolarization. During depolarization, voltage-gated sodium ion channels open, increasing the neuron's membrane conductance for sodium ions and depolarizing the cell's membrane potential (from typically -70 mV toward a positive potential). In other words, the membrane is made less negative.

  9. Excitatory postsynaptic potential - Wikipedia

    en.wikipedia.org/wiki/Excitatory_postsynaptic...

    In neuroscience, an excitatory postsynaptic potential (EPSP) is a postsynaptic potential that makes the postsynaptic neuron more likely to fire an action potential. This temporary depolarization of postsynaptic membrane potential , caused by the flow of positively charged ions into the postsynaptic cell, is a result of opening ligand-gated ion ...