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  2. Spironolactone - Wikipedia

    en.wikipedia.org/wiki/Spironolactone

    [121] [122] The risk of hyperkalemia with spironolactone is greatest in the elderly, in people with renal impairment (e.g., due to chronic kidney disease or diabetic nephropathy), in people taking certain other medications (including ACE inhibitors, angiotensin II receptor blockers, nonsteroidal anti-inflammatory drugs, the antibiotic ...

  3. Spirolactone - Wikipedia

    en.wikipedia.org/wiki/Spirolactone

    Spirolactones are a class of functional group in organic chemistry featuring a cyclic ester attached spiro to another ring system. The name is also used to refer to a class of synthetic steroids, called steroid-17α-spirolactones, 17α-spirolactosteroids, or simply 17α-spirolactones, which feature their spirolactone group at the C17α position.

  4. 6β-Hydroxy-7α-thiomethylspironolactone - Wikipedia

    en.wikipedia.org/wiki/6β-Hydroxy-7α...

    Spironolactone is a prodrug with a short terminal half-life of 1.4 hours. [ 5 ] [ 6 ] [ 7 ] The active metabolites of spironolactone have extended terminal half-lives of 13.8 hours for 7α-TMS, 15.0 hours for 6β-OH-7α-TMS, and 16.5 hours for canrenone, and accordingly, these metabolites are responsible for the therapeutic effects of the drug.

  5. Physicians' Desk Reference - Wikipedia

    en.wikipedia.org/wiki/Physicians'_Desk_Reference

    The book was distributed for free to all licensed medical doctors in America; only drugs which drug manufacturers paid to appear, appeared in the PDR, and no generic drugs were listed. The 71st Edition, published in 2017, was the final hardcover edition, weighed in at 4.6 pounds (2.1 kg) and contained information on over 1,000 drugs. [ 1 ]

  6. Spironolactone: 11 things a dermatologist wants you to know ...

    www.aol.com/news/spironolactone-11-things...

    Here, a dermatologist explains what you need to know about Spironolactone. Skip to main content. Sign in. Mail. 24/7 Help. For premium support please call: 800-290-4726 more ways to reach ...

  7. Drugs.com - Wikipedia

    en.wikipedia.org/wiki/Drugs.com

    Drugs.com is an online pharmaceutical encyclopedia that provides drug information for consumers and healthcare professionals, primarily in the United States. It self-describes its information as "accurate and independent" yet limited to being "for educational purposes only and is not intended for medical advice, diagnosis or treatment." [1]