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This list of over 500 monoclonal antibodies includes approved and investigational drugs as well as drugs that have been withdrawn from market; consequently, the column Use does not necessarily indicate clinical usage. See the list of FDA-approved therapeutic monoclonal antibodies in the monoclonal antibody therapy page.
Pages in category "Antibody-drug conjugates" The following 57 pages are in this category, out of 57 total. This list may not reflect recent changes. ...
Schematic structure of an antibody–drug conjugate (ADC) Antibody–drug conjugates or ADCs are a class of biopharmaceutical drugs designed as a targeted therapy for treating cancer. [1] Unlike chemotherapy, ADCs are intended to target and kill tumor cells while sparing healthy cells. As of 2019, some 56 pharmaceutical companies were ...
The first FDA-approved therapeutic monoclonal antibody was a murine IgG2a CD3 specific transplant rejection drug, OKT3 (also called muromonab), in 1986. This drug found use in solid organ transplant recipients who became steroid resistant. [39] Hundreds of therapies are undergoing clinical trials. Most are concerned with immunological and ...
CiteAb started in 2013 as an academic project by Dr Andrew Chalmers, a senior lecturer at the University of Bath. [1] The resource was established to help scientific researchers find suitable antibodies for their experiments - such antibodies can be helpful in context of screenings, therapeutic development, and drug discovery.
The main drug types in TTD include small molecule, antibody, nucleic acid drug, cell therapy, gene therapy and vaccine. Small molecule : the most common medications in the pharmaceutical market Antibody : includes monoclonal antibodies and several alternatives such as antibody-drug conjugates, bispecific antibodies, IgG mixtures, and antibody ...