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Colloids contain larger insoluble molecules, such as gelatin; blood itself is a colloid. There is no evidence that colloids are better than crystalloids in those who have had trauma, burns, or surgery. Colloids are more expensive than crystalloids. As such, colloids are not recommended for volume expansion in these settings. [2]
Hydroxyethyl starch (HES/HAES), sold under the brand name Voluven among others, is a nonionic starch derivative, used as a volume expander in intravenous therapy.The use of HES on critically ill patients is associated with an increased risk of death and kidney problems.
A colloid has a dispersed phase (the suspended particles) and a continuous phase (the medium of suspension). The dispersed phase particles have a diameter of approximately 1 nanometre to 1 micrometre. [2] [3] Some colloids are translucent because of the Tyndall effect, which is the scattering of light by particles in
Intravenous therapy (abbreviated as IV therapy) is a medical technique that administers fluids, medications and nutrients directly into a person's vein.The intravenous route of administration is commonly used for rehydration or to provide nutrients for those who cannot, or will not—due to reduced mental states or otherwise—consume food or water by mouth.
Crystalloid solutions shows little difference with hydroxyethyl starch in terms of risk of death. [66] Starches also carry an increased risk of acute kidney injury, [66] [67] and need for blood transfusion. [68] [69] Various colloid solutions (such as modified gelatin) carry no advantage over crystalloid. [66]
Fluid replacement or fluid resuscitation is the medical practice of replenishing bodily fluid lost through sweating, bleeding, fluid shifts or other pathologic processes. . Fluids can be replaced with oral rehydration therapy (drinking), intravenous therapy, rectally such as with a Murphy drip, or by hypodermoclysis, the direct injection of fluid into the subcutaneous tis
Timing is important to wound healing. Critically, the timing of wound re-epithelialization can decide the outcome of the healing. [11] If the epithelization of tissue over a denuded area is slow, a scar will form over many weeks, or months; [12] [13] If the epithelization of a wounded area is fast, the healing will result in regeneration.
Crystalloid may refer to: A substance that, when dissolved, forms a true solution and is able to pass through a semipermeable membrane. They get separated from colloids during dialysis.