Ad
related to: what is a cardiac glycoside function meter
Search results
Results From The WOW.Com Content Network
Cardiac glycosides affect the sodium-potassium ATPase pump in cardiac muscle cells to alter their function. [1] Normally, these sodium-potassium pumps move potassium ions in and sodium ions out. Cardiac glycosides, however, inhibit this pump by stabilizing it in the E2-P transition state, so that sodium cannot be extruded: intracellular sodium ...
Cardiac glycosides like digoxin, primarily inhibit the sodium-potassium pump (Na+/K+ ATPase), an important protein located on the surface of cardiomyocytes (cardiac muscle cells). [ 1 ] [ 2 ] Using ATP (the cell’s energy currency), this protein facilitates the transport of extracellular potassium ions (K+) into the cell while exporting sodium ...
These are a type of cardiac glycoside, the other being the cardenolide glycosides. Both bufadienolides and their glycosides are toxic; specifically, they can cause an atrioventricular block, bradycardia (slow heartbeat), ventricular tachycardia (a type of rapid heartbeat), and possibly lethal cardiac arrest. [1]
Ouabain is a cardiac glycoside that acts by non-selectively inhibiting the Na + /K +-ATPase sodium–potassium ion pump. [2] Once ouabain binds to this enzyme, the enzyme ceases to function, leading to an increase of intracellular sodium.
Digitoxin is a cardiac glycoside used for the treatment of heart failure and certain kinds of heart arrhythmia. It is a phytosteroid and is similar in structure and effects to digoxin, though the effects are longer-lasting. Unlike digoxin, which is eliminated from the body via the kidneys, it is eliminated via the liver, and so can be used in ...
Pages in category "Cardiac glycosides" The following 8 pages are in this category, out of 8 total. This list may not reflect recent changes. ...
Cerberin is a type of cardiac glycoside, found in the seeds of the dicotyledonous angiosperm genus Cerbera; including the suicide tree (Cerbera odollam) and the sea mango (Cerbera manghas). As a cardiac glycoside, cerberin disrupts the function of the heart by blocking its sodium and potassium ATPase. [2]
Cardiac markers are biomarkers measured to evaluate heart function. They can be useful in the early prediction or diagnosis of disease. [ 1 ] Although they are often discussed in the context of myocardial infarction , other conditions can lead to an elevation in cardiac marker level.