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Nail clubbing, also known as digital clubbing or clubbing, is a deformity of the finger or toe nails associated with a number of diseases, anomalies and defects, some congenital, mostly of the heart and lungs. [2] [3] When it occurs together with joint effusions, joint pains, and abnormal skin and bone growth it is known as hypertrophic ...
This is why acroosteolysis and periosteal bone formation can be explained by the action of PGE 2. [10] Furthermore, PGE 2 has vasodilatory effects, which is consistent with prolonged local vasodilation in digital clubbing. [10] Elevated levels of PGE 2 in PDP patients are associated with mutations of HPGD gene. These patients showed typical PDP ...
White dog shaker syndrome causes full body tremors in small, white dog breeds. It is most common in West Highland White Terriers, Maltese, Bichons, and Poodles. [6] Wobbler disease (cervical instability) is a condition of the cervical vertebrae that causes an unsteady gait and weakness in dogs.
Acropachy is a dermopathy associated with Graves' disease. [1] It is characterized by soft-tissue swelling of the hands and clubbing of the fingers. Radiographic imaging of affected extremities typically demonstrates periostitis, most commonly the metacarpal bones.
Other changes may include feeling tired, and clubbing abnormally large and dome shaped finger and toenails. [1] Complications may include pulmonary hypertension, heart failure, pneumonia or pulmonary embolism. [1] The cause is unknown, hence the term idiopathic. [2]
Eisenmenger syndrome or Eisenmenger's syndrome is defined as the process in which a long-standing left-to-right cardiac shunt caused by a congenital heart defect (typically by a ventricular septal defect, atrial septal defect, or less commonly, patent ductus arteriosus) causes pulmonary hypertension [1] [2] and eventual reversal of the shunt into a cyanotic right-to-left shunt.
Hypertrophic osteoarthropathy is a medical condition combining clubbing and periostitis of the small hand joints, especially the distal interphalangeal joints and the metacarpophalangeal joints. Distal expansion of the long bones as well as painful, swollen joints [3] and synovial villous proliferation are often seen.
The canine distemper vaccination in particular has been a suspected causal factor due to the significant number of overlapping symptoms observed between systemically affected HOD puppies and dogs suffering from distemper, [9] but to-date, no definitive linkage has been demonstrated. [10] The cause of canine HOD largely remains unknown.