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Pituitary pars intermedia dysfunction (PPID), or equine Cushing's disease, is an endocrine disease affecting the pituitary gland of horses. It is most commonly seen in older animals, [ 1 ] and is classically associated with the formation of a long, wavy coat ( hirsutism ) and chronic laminitis .
Cushing's is an umbrella term for conditions caused by elevated cortisol and adrenocorticotropic hormone levels. Cushing's disease most commonly refers to pituitary-dependent hyperadrenocorticism, the most common condition of Cushing's syndrome, but 'Cushing's' is used to refer to all hyperadrenocorticism conditions. [2]
Vitex agnus-castus (also called vitex, chaste tree / chastetree, chasteberry, Abraham's balm, [1] lilac chastetree, [2] or monk's pepper) is a plant native of the Mediterranean region. It is one of the few temperate-zone species of Vitex , which is on the whole a genus of tropical and subtropical flowering plants . [ 3 ]
Nirgundi Plant with bluish-purple flowers In vitro flowering in Vitex negundo Inflorescence of Vitex negundo in Panchkhal valley in Nepal. Vitex negundo, commonly known as the Chinese chaste tree, [2] five-leaved chaste tree, or horseshoe vitex, or nisinda is a large aromatic shrub with quadrangular, densely whitish, tomentose branchlets.
Equine metabolic syndrome (EMS) is an endocrinopathy affecting horses and ponies. It is of primary concern due to its link to obesity, insulin dysregulation , and subsequent laminitis .
Vitex / ˈ v aɪ t ɛ k s / [3] is a genus of flowering plants in the sage family Lamiaceae.It has about 250 species. [4] [5] Common names include chaste tree or chastetree, traditionally referring to V. agnus-castus, but often applied to other species, as well.