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Combined intracavernous injection and stimulation test or CIS test is the most commonly performed office diagnostic procedure for erectile dysfunction. It consists of an intracavernosal injection , visual or manual sexual stimulation , and a rating of the subsequent erection .
Trimix is a combination of three drugs: alprostadil, papaverine, and phentolamine. These medications work in combination to increase blood flow to the penis, resulting in an erection. [1] [2] [3] Alprostadil is a prostaglandin vasodilator that allows more blood to flow into the area by relaxing the smooth muscle in the blood vessels of the penis.
An intracavernous (or intracavernosal) injection is an injection into the base of the penis. This injection site is often used to administer medications to check for or treat erectile dysfunction in adult men (in, for example, a combined intracavernous injection and stimulation test ). [ 1 ]
Erectile dysfunction (ED), also referred to as impotence, is a form of sexual dysfunction in males characterized by the persistent or recurring inability to achieve or maintain a penile erection with sufficient rigidity and duration for satisfactory sexual activity.
Venous leak, also called venogenic erectile dysfunction and penile venous insufficiency, is one category of vascular-induced (vasculogenic) impotence – a cause of erectile dysfunction in males. [2] It affects all ages, being particularly awkward in young men. [ 3 ]
Erectile dysfunction (ED), or impotence, is a sexual dysfunction characterized by the inability to develop or maintain an erection of the penis. There are various underlying causes of ED, including damage to anatomical structures, psychological causes, medical disease, and drug use.