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Difference between Z-test and t-test: Z-test is used when sample size is large (n>50), or the population variance is known. t-test is used when sample size is small (n<50) and population variance is unknown. There is no universal constant at which the sample size is generally considered large enough to justify use of the plug-in test.
The Z-factor defines a characteristic parameter of the capability of hit identification for each given assay. The following categorization of HTS assay quality by the value of the Z-Factor is a modification of Table 1 shown in Zhang et al. (1999); [2] note that the Z-factor cannot exceed one.
Comparison of the various grading methods in a normal distribution, including: standard deviations, cumulative percentages, percentile equivalents, z-scores, T-scores. In statistics, the standard score is the number of standard deviations by which the value of a raw score (i.e., an observed value or data point) is above or below the mean value of what is being observed or measured.
A statistical hypothesis test compares a test statistic (z or t for examples) to a threshold. The test statistic (the formula found in the table below) is based on optimality. The test statistic (the formula found in the table below) is based on optimality.
Example: Prob(Z ≤ 0.69) = 0.7549. Complementary cumulative gives a probability that a statistic is greater than Z. This equates to the area of the distribution above Z. Example: Find Prob(Z ≥ 0.69). Since this is the portion of the area above Z, the proportion that is greater than Z is found by subtracting Z from 1.
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The table shown on the right can be used in a two-sample t-test to estimate the sample sizes of an experimental group and a control group that are of equal size, that is, the total number of individuals in the trial is twice that of the number given, and the desired significance level is 0.05. [4]
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