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Symptoms of advanced cervical cancer may include loss of appetite, weight loss, fatigue, pelvic pain, back pain, leg pain, swollen legs, heavy vaginal bleeding, bone fractures, and (rarely) leakage of urine or faeces from the vagina. [39] Bleeding after douching or after a pelvic exam is a common symptom of cervical cancer. [40]
One in 142 women in the UK will be diagnosed with cervical cancer in their lifetime
The cause of CIN is chronic infection of the cervix with HPV, especially infection with high-risk HPV types 16 or 18. It is thought that the high-risk HPV infections have the ability to inactivate tumor suppressor genes such as the p53 gene and the RB gene, thus allowing the infected cells to grow unchecked and accumulate successive mutations, eventually leading to cancer.
Unusual vaginal bleeding between periods or after menopause among main symptoms
Cervical intraepithelial neoplasia is a possible result of the biopsy and represents dysplastic changes that may eventually progress to invasive cancer. [53] Most cases of cervical cancer are detected in this way, without having caused any symptoms. When symptoms occur, they may include vaginal bleeding, discharge, or discomfort. [54]
Cervical health and period-related pain can be discussed with your healthcare provider to weigh out a few options. "Going on birth control can help you manage your period symptoms," says Dr. Mysore.