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Spasticity is often treated with the drug baclofen, which acts as an agonist at GABA receptors, which are inhibitory. Spastic cerebral palsy is the most common form of cerebral palsy, which is a group of permanent movement problems that do not get worse over time. GABA's inhibitory actions contribute to baclofen's efficacy as an anti-spasticity ...
Spastic cerebral palsy is caused by malformation of or damage to the parts of the brain that control movement. [12] What exactly makes some children susceptible to such brain damage is often unknown but it is believed that cerebral palsy may be the result of causal pathways, or chains of events that cause or increase the likelihood of brain injury. [13]
The muscle spasticity can cause gait patterns to be awkward and jerky. The constant spastic state of the muscle can lead to bone and tendon deformation, further complicating the patient's mobility. Many patients with spastic hemiplegia use canes, walkers and even wheelchairs.
Spastic diplegia is a form of cerebral palsy (CP) that primarily affects the legs, with possible considerable asymmetry between the two sides. It is a chronic neuromuscular condition of hypertonia and spasticity in the muscles of the lower extremities of the human body, manifested as an especially high and constant "tightness" or "stiffness", [1] [2] usually in the legs, hips and pelvis.
In medicine, the adjective spastic refers to an alteration in muscle tone affected by the medical condition spasticity, which is a well-known symptomatic phenomenon seen in patients with a wide range of central neurological disorders, including spinal cord injury, cerebral palsy (for example, spastic diplegia), stroke, amyotrophic lateral sclerosis (ALS), and multiple sclerosis (MS), [1] as ...
Hypertonia is a term sometimes used synonymously with spasticity and rigidity in the literature surrounding damage to the central nervous system, namely upper motor neuron lesions. [1] Impaired ability of damaged motor neurons to regulate descending pathways gives rise to disordered spinal reflexes , increased excitability of muscle spindles ...
Spastic paraplegia: Spasticity (excessive and inappropriate muscle activation) and weakness in the lower limbs leading to a shuffling gait and difficulty walking. Lower extremities are affected earlier, and with higher severity than upper extremities. Dystonia: abnormally increased muscular tone that causes fixed abnormal postures [2]
A spasm is a sudden involuntary contraction of a muscle, [1] a group of muscles, or a hollow organ, such as the bladder.. A spasmodic muscle contraction may be caused by many medical conditions, including dystonia.
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