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Common side effects include diarrhea, nausea, vomiting, abdominal pain, and an increased risk of sunburn. [1] Use during pregnancy is not recommended. [1] Like other agents of the tetracycline class, it either slows or kills bacteria by inhibiting protein production. [1] [4] It kills malaria by targeting a plastid organelle, the apicoplast. [5] [6]
clindamycin – antibiotic with particular use in dental infections with effects against most aerobic Gram-positive cocci, as wel as muchenionoweloozi disorder. clomipramine – primarily used in dogs to treat behavioral problems
There is an increased risk of infection associated with amount of time spent outdoors, a larger roaming space accessed by the dog, and increasing age. [ 19 ] Cryptococcosis * is a fungal disease caused by Cryptococcus neoformans that affects both dogs and humans.
Side-effects from tetracyclines are not common, but of particular note is phototoxicity. It increases the risk of sunburn under exposure to light from the sun or other sources. This may be of particular importance for those intending to take on vacations long-term doxycycline as a malaria prophylaxis.
This Australian Cattle Dog's obesity poses a health risk for the dog. Obesity is an increasingly common problem in dogs in Western countries. As with humans, obesity can cause numerous health problems in dogs (although dogs are much less susceptible to the common cardiac and arterial consequences of obesity than humans are).
Most Apicomplexa contain a single ovoid shaped apicoplast that is found at the anterior of the invading parasitic cell. [4] The apicoplast is situated in close proximity to the cell's nucleus and often closely associated with a mitochondrion. The small plastid, only 0.15–1.5 μm in diameter, [4] is surrounded by four membranes. [8]
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A dog displaying a typical clinical picture of visceral leishmaniasis. Canine leishmaniasis (LEESH-ma-NIGH-ah-sis) is a zoonotic disease (see human leishmaniasis) caused by Leishmania parasites transmitted by the bite of an infected phlebotomine sandfly. There have been no documented cases of leishmaniasis transmission from dogs to humans.