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Styrene oxide is a main metabolite of styrene in humans or animals, resulting from oxidation by cytochrome P450. It is considered possibly carcinogenic from gavaging significant amounts into mice and rats. [4] Styrene oxide is subsequently hydrolyzed in vivo to styrene glycol by epoxide hydrolase. [5]
Residents near Cleves are being urged to leave their homes Tuesday afternoon because a rail car is leaking styrene. What to know about the chemical.
Styrene is regarded as a "known carcinogen", especially in case of eye contact, but also in case of skin contact, of ingestion and of inhalation, according to several sources. [20] [33] [34] [35] Styrene is largely metabolized into styrene oxide in humans, resulting from oxidation by cytochrome P450.
Here's what the Drug & Poison Information Center at Cincinnati Children’s Hospital advises regarding returning home following the styrene leak.
In August 2005, styrene began leaking from a railcar in Cincinnati's East End. That also was not the result of a derailment, but the leak forced evacuations and shelter-in-place orders for residents.
The Visakhapatnam gas leak, also referred to as the Vizag gas leak, was an industrial accident that occurred at the LG Polymers chemical plant in the R. R. Venkatapuram village of the Gopalapatnam neighbourhood, located at the outskirts of Visakhapatnam, Andhra Pradesh, India, during the early morning of 7 May 2020.
Health effects of pesticides may be acute or delayed in those who are exposed. [1] Acute effects can include pesticide poisoning, which may be a medical emergency. [2] Strong evidence exists for other, long-term negative health outcomes from pesticide exposure including birth defects, fetal death, [3] neurodevelopmental disorder, [4] cancer, and neurologic illness including Parkinson's disease ...
Health effects for non-smokers must be considered in absolute terms for long-term use as well as the risk of transition into traditiion cigarettes, while for smokers the relative risks are paramount, and if used as a quitting aid, any effects of short-term use are most important.