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  2. Eplerenone - Wikipedia

    en.wikipedia.org/wiki/Eplerenone

    Eplerenone differs from spironolactone in its extensive metabolism, with a short half-life and inactive metabolites. [4] Eplerenone seems to be about 50 to 75% as potent as spironolactone as an antimineralocorticoid. [24] Hence, 25 mg/day spironolactone may be equivalent to approximately 50 mg/day eplerenone. [25]

  3. Etacrynic acid - Wikipedia

    en.wikipedia.org/wiki/Etacrynic_acid

    The ethacrynic acid tablet market had U.S. sales of approximately $17 million for the 12 months ending April 2020 according to IQVIA. [ 5 ] National Average Drug Acquisition Cost data from the Centers for Medicare and Medicaid Services [ 6 ] shows that the average price paid by retail pharmacies for an Edecrin 25 MG tablet was $5.24 as 11/28/13 ...

  4. Esaxerenone - Wikipedia

    en.wikipedia.org/wiki/Esaxerenone

    Daiichi Sankyo Company, Limited on January 8, 2019 announced the receipt of marketing approval in Japan for MINNEBROTM Tablets 1.25 mg, 2.5 mg and 5 mg (generic name: esaxerenone) for the treatment of hypertension. As of January 2019, esaxerenone is in phase III clinical trials for diabetic nephropathies. [1] [4]

  5. Potassium-sparing diuretic - Wikipedia

    en.wikipedia.org/wiki/Potassium-sparing_diuretic

    Potassium-sparing diuretics act to prevent sodium reabsorption in the collecting tubule by either binding ENaCs (amiloride, triamterene) or by inhibiting aldosterone receptors (spironolactone, eplerenone). This prevents excessive excretion of K + in urine and decreased retention of water, preventing hypokalemia. [10]

  6. Spironolactone - Wikipedia

    en.wikipedia.org/wiki/Spironolactone

    Conversely, in studies of healthy men given high-dose spironolactone, gynecomastia occurred in 3 of 10 (30%) at 100 mg/day, in 5 of 8 (62.5%) at 200 mg/day, and in 6 of 9 (66.7%) at 400 mg/day, relative to none of 12 controls. [134] [135] The severity of gynecomastia with spironolactone varies considerably, but is usually mild. [110]

  7. How to Pay the Lowest Price for Cialis & Tadalafil - AOL

    www.aol.com/lifestyle/pay-lowest-price-cialis...

    The price of generic tadalafil can vary based on the dosage, but most versions of generic tadalafil cost $10 to $13 per tablet. When used daily, generic tadalafil can be less than $3 per pill ($79 ...