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A major systematic review and network meta-analysis of medications for the treatment of insomnia published in 2022 found that doxylamine had an effect size (standardized mean difference (SMD)) against placebo for treatment of insomnia at 4 weeks of 0.47 (95% CI Tooltip confidence interval 0.06 to 0.89). [14]
Sleep Medicine Reviews is a bimonthly peer-reviewed medical journal covering research on the diagnosis and therapy of sleep disturbances and disorders (sleep medicine). It was established in 1997 and is published by Elsevier. The editors-in-chief are J. Krieger (Louis Pasteur University) and Michael V Vitiello (University of Washington).
Zolpidem, sold under the brand name Ambien among others, is a medication primarily used for the short-term treatment of sleeping problems. [11] [16] Guidelines recommend that it be used only after cognitive behavioral therapy for insomnia and after behavioral changes, such as sleep hygiene, have been tried.
A 2023 systematic review [39] demonstrated that just stimulus control and sleep restriction are effective treatment options for insomnia in older adults. It also indicated that when combined, they generate improvements with a magnitude similar to that of full CBT-I, in as little as two therapeutic sessions.
Sleep is a monthly peer-reviewed medical journal covering research on sleep. Topics include basic and neuroscience studies of sleep, in vitro and animal models of sleep, studies in clinical or population samples, clinical trials, and epidemiologic studies. It is the official journal of the Sleep Research Society.
Ramelteon, sold under the brand name Rozerem among others, is a melatonin agonist medication which is used in the treatment of insomnia. [3] [5] It is indicated specifically for the treatment of insomnia characterized by difficulties with sleep onset. [3]
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