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Generally scores below 0.20 corresponds to randomly chosen unrelated proteins whereas structures with a score higher than 0.5 assume roughly the same fold. [2] A quantitative study [3] shows that proteins of TM-score = 0.5 have a posterior probability of 37% in the same CATH topology family and of 13% in the same SCOP fold family. The ...
TM-score – a different structure comparison measure; Longest continuous segment (LCS) — A different structure comparison measure; Global distance calculation (GDC_sc, GDC_all) — Structure comparison measures that use full-model information (not just α-carbon) to assess similarity
TM-align TM-score based protein structure alignment: Cα: Pair: nil: server and download: Y. Zhang & J. Skolnick: 2005 mTM-align Multiple protein structure alignment based on TM-align Cα Multi No server and download: R. Dong, Z. Peng, Y. Zhang & J. Yang 2018 VAST Vector Alignment Search Tool: SSE: Pair: nil: server: S. Bryant: 1996 PrISM
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The score combines the log-likelihood of the alignment, a covariation term and the basepair probabilities. any: Yes: Yes: No: sourcecode [67] [68] Multilign: This method uses multiple Dynalign calculations to find a low free energy structure common to any number of sequences. It does not require any sequence identity. any: Yes: Yes: No ...
I-TASSER is a template-based method for protein structure and function prediction. [1] The pipeline consists of six consecutive steps: 1, Secondary structure prediction by PSSpred
By the original design the GDT algorithm calculates 20 GDT scores, i.e. for each of 20 consecutive distance cutoffs (0.5 Å, 1.0 Å, 1.5 Å, ... 10.0 Å). [2] For structure similarity assessment it is intended to use the GDT scores from several cutoff distances, and scores generally increase with increasing cutoff.
VantageScore 3.0, with scores ranging from 300 to 850, is a user-friendly credit score model developed by the three major nationwide credit reporting agencies, Experian ®, TransUnion ®, and ...