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Mammillary bodies, and their projections to the anterior thalamus via the mammillothalamic tract, are important for recollective memory. [7] According to studies of rats with mammillary body lesions, damage to the medial mammillary nucleus lead to spatial memory deficits.
The mammillothalamic tract is part of the Papez circuit (involved in spatial memory), starting and finishing in the hippocampus. [1] The fibers of the MMT are heavily myelinated. [2] [3] [4] It arises from the medial and lateral nuclei of the mammillary bodies, and from fibers that are directly continued from the fornix of the hippocampus.
The anterior nuclei receive afferents from the hippocampus and subiculum directly via the fornix, and indirectly via the mammillary bodies and mammillothalamic tract (MTT). They send efferent fibers to the cingulate gyrus, limbic, and orbitofrontal cortex. [1] The anterior nuclei of the thalamus display functions pertaining to memory.
Some scientists have narrowed it down to specifically spatial and episodic memory. [9] [10] Damage to the mammillothalamic tract, ventral anterior nucleus, and ventral lateral nucleus can result in memory and language impairment. [11] Amnesia can be a result of disconnection of the mammillary bodies from the Papez circuit. [12]
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The medial dorsal nucleus (or mediodorsal nucleus of thalamus, dorsomedial nucleus, dorsal medial nucleus, or medial nucleus group) is a large nucleus in the thalamus. [1] [2] It is separated from the other thalamic nuclei by the internal medullary lamina.
Mammillary body, a part of the brain; Mammillary process, a tubercle on the lumbar vertebrae; Mammillaria (disambiguation) This page was last edited on 31 ...