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Hypoesthesia or numbness is a common side effect of various medical conditions that manifests as a reduced sense of touch or sensation, or a partial loss of sensitivity to sensory stimuli. In everyday speech this is generally referred to as numbness.
Reactive hyperaemia, which occurs when blood flow is restored after a period of ischemia, may be accompanied by paresthesia, e.g. when patients with Raynaud's disease rewarm after a cold episode. [3] Cases of paresthesia have also been reported at varying frequencies following anthrax, [4] flu, [5] [6] HPV [7] and COVID-19 [8] [9] vaccine intake.
The condition can cause localized pain, discoloration (paleness), and sensations of cold and/or numbness. When exposed to cold temperatures, the blood supply to the fingers or toes, and in some cases the nose or earlobes, is markedly reduced; the skin turns pale or white (called pallor) and becomes cold and numb.
Along with feeling cold, if you notice “your hands have significant color change, numbness, weakness or pain, it could be from an underlying vascular disease, neurologic problems or Raynaud’s ...
If you struggle with chronically cold hands, there are a few general measures you can take to manage your symptoms. First, you should always try to minimize exposure to cold temperatures.
Chemotherapy-induced peripheral neuropathy is a progressive, enduring and often irreversible tingling numbness, intense pain, and hypersensitivity to cold, beginning in the hands and feet and sometimes involving the arms and legs caused by some chemotherapy agents. [7]
It does not require exposure to cold to develop. Levamisole toxicity is a vasculitis that can appear similar to frostbite. [18] It is caused by contamination of cocaine by levamisole. Skin lesions can look similar those of frostbite, but do not require cold exposure to occur. People who have hypothermia often have frostbite as well. [10]
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