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2-Octyl cyanoacrylate is a cyanoacrylate ester typically used as a wound closure adhesive (under the brand name Dermabond). [1] It is closely related to octyl cyanoacrylate . The use of 2-octyl cyanoacrylate was approved in 1998; offered as an alternative to stitches, sutures, and or adhesive strips.
In the US, due to its potential to irritate the skin, the U.S. Food and Drug Administration (FDA) did not approve its use as a medical adhesive until 1998 with Dermabond (2-octyl cyanoacrylate). [8] A 1986 independent study suggests that cyanoacrylate can be safer and more functional for wound closure than traditional suturing (stitches). [9]
A dermal adhesive (or skin glue) is a glue used to close wounds in the skin as an alternative to sutures, staples, or clips. Glued closure results in less scarring and is less prone to infection than sutured or stapled closure. There is also no residual closure to remove, so follow-up visits for removal are not required.
The medical applications of butyl cyanoacrylate include its use as an adhesive for lacerations of the skin, [5] and in the treatment of bleeding from vascular structures. . Butyl cyanoacrylate has been used to treat arteriovenous malformations [6] by application of the glue into the abnormality through angiog
There are three cyanoacrylate compounds currently available as topical skin adhesives. 2-Octyl cyanoacrylate is marketed as Dermabond, SurgiSeal, and more recently LiquiBand Exceed. n-Butyl cyanoacrylate is marketed as Histoacryl, Indermil, GluStitch, GluSeal, PeriAcryl, and LiquiBand. The compound ethyl 2-cyanoacrylate is available as Epiglu. [3]
Liquid bandage is a topical skin treatment for minor wounds which binds to the skin to form a protective polymeric layer that keeps dirt and germs out and moisture in. [1] It can be directly applied to the wound after removing debris.