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Itching, bleeding and crust formation may occur in some. [2] The backs and shoulders of males and legs of women are particularly prone. [2] It is a type of melanocytic tumor occurring in intermittently sun-exposed skin. [2] The cause is associated with repeated sunburns in childhood, intermittent exposure to sun during life, and sun bed use. [2]
Melanoma is the most dangerous type of skin cancer; it develops from the melanin-producing cells known as melanocytes. [1] It typically occurs in the skin, but may rarely occur in the mouth, intestines, or eye (uveal melanoma). [1] [2] In women, melanomas most commonly occur on the legs; while in men, on the back. [2]
Skin cancer is the most common form of cancer, globally accounting for at least 40% of cancer cases. [5] [20] The most common type is nonmelanoma skin cancer, which occurs in at least 2–3 million people per year. [6] [21] This is a rough estimate; good statistics are not kept. [1]
A light-colored or non-pigmented NM lesion may escape detection because the appearance is not alarming, however an ulcerated and/or bleeding lesion is common. [3]: 696 Polypoid melanoma is a virulent variant of nodular melanoma. [3]: 696 The microscopic hallmarks are: Dome-shaped at low power; Epidermis thin or normal
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The skin weighs an average of four kilograms, covers an area of two square metres, and is made of three distinct layers: the epidermis, dermis, and subcutaneous tissue. [1] The two main types of human skin are: glabrous skin , the hairless skin on the palms and soles (also referred to as the "palmoplantar" surfaces), and hair-bearing skin. [ 3 ]
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