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  2. Upper motor neuron lesion - Wikipedia

    en.wikipedia.org/wiki/Upper_motor_neuron_lesion

    Conversely, a lower motor neuron lesion affects nerve fibers traveling from the anterior horn of the spinal cord or the cranial motor nuclei to the relevant muscle(s). [ 1 ] Upper motor neuron lesions occur in the brain or the spinal cord as the result of stroke , multiple sclerosis , traumatic brain injury , cerebral palsy , atypical ...

  3. Upper motor neuron syndrome - Wikipedia

    en.wikipedia.org/wiki/Upper_motor_neuron_syndrome

    The upper motor neuron syndrome signs are seen in conditions where motor areas in the brain and/or spinal cord are damaged or fail to develop normally. These include spinal cord injury, cerebral palsy, multiple sclerosis and acquired brain injury including stroke.

  4. Upper motor neuron - Wikipedia

    en.wikipedia.org/wiki/Upper_motor_neuron

    Any upper motor neuron lesion, also known as pyramidal insufficiency, occurs in the neural pathway above the anterior horn of the spinal cord.Such lesions can arise as a result of stroke, multiple sclerosis, spinal cord injury or other acquired brain injury.

  5. Motor neuron diseases - Wikipedia

    en.wikipedia.org/wiki/Motor_neuron_diseases

    Motor neuron diseases are on a spectrum in terms of upper and lower motor neuron involvement. [6] Some have just lower or upper motor neuron findings, while others have a mix of both. Lower motor neuron (LMN) findings include muscle atrophy and fasciculations , and upper motor neuron (UMN) findings include hyperreflexia , spasticity, muscle ...

  6. Multiple sclerosis - Wikipedia

    en.wikipedia.org/wiki/Multiple_sclerosis

    Multiple sclerosis (MS) is an autoimmune disease resulting in damage to the insulating covers of nerve cells in the brain and spinal cord. [3] As a demyelinating disease , MS disrupts the nervous system's ability to transmit signals , resulting in a range of signs and symptoms , including physical, mental , and sometimes psychiatric problems.

  7. Myelopathy - Wikipedia

    en.wikipedia.org/wiki/Myelopathy

    Upper motor neuron signs—weakness, spasticity, clumsiness, altered tonus, hyperreflexia and pathological reflexes, including Hoffmann's sign and inverted plantar reflex (positive Babinski sign) Lower motor neuron signs—weakness, clumsiness in the muscle group innervated at the level of spinal cord compromise, muscle atrophy, hyporeflexia ...

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